|Contents||Vial: PEG MGF (IGF 1Ec) 2mg for IM or SC use .
Ampoule: 2ml Sterile water for injection.
|Administration||Intramuscular or Subcutaneous injection.|
|Storage||Store at room temperature away from heat and direct sunlight pre reconstitution. Refrigerate between 2-8’C post Reconstitution.|
|Dosage||Initial: 5 mcg/kg/Day. May increase dose gradually. Max: 20 mcg/kg/day.|
|Contraindications||Acute critical illness due to heart or abdominal surgery, multiple accidental trauma or respiratory failure; active neoplasms, proliferative or preproliferative diabetic retinopathy; lactation; patients with closed epiphyses. Intracranial lesions. Patients with Prader-Willi syndrome who are severely obese or have severe respiratory impairment.|
|Special Precautions||Monitor thyroid function; benign intracranial hypertension. DM; may require dose reduction in insulin. Pregnancy. Discontinue treatment if there is evidence of tumour growth. Monitoring in patients with scoliosis is recommended due to risk of progression of scoliosis.|
|Adverse Drug Reactions||Side effects noted are tiredness, feeling of lethargy, head rush or euphoria.|
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