Vial: PEG MGF (IGF 1Ec), 2mg. Ampoule: 2ml Sterile water for injection.
Administration
Intramuscular or Subcutaneous injection.
Storage
Store at room temperature away from heat and direct sunlight pre reconstitution. Refrigerate between 2-8’C post Reconstitution.
Dosage
Initial: 5 mcg/kg/Day. May increase dose gradually. Max: 20 mcg/kg/day.
Contraindications
Acute critical illness due to heart or abdominal surgery, multiple accidental trauma or respiratory failure; active neoplasms, proliferative or preproliferative diabetic retinopathy; lactation; patients with closed epiphyses. Intracranial lesions. Patients with Prader-Willi syndrome who are severely obese or have severe respiratory impairment.
Special Precautions
Monitor thyroid function; benign intracranial hypertension. DM; may require dose reduction in insulin. Pregnancy. Discontinue treatment if there is evidence of tumour growth. Monitoring in patients with scoliosis is recommended due to risk of progression of scoliosis.
Adverse Drug Reactions
Side effects noted are tiredness, feeling of lethargy, head rush or euphoria.
Drug Interactions
NA
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